Summary
Accumulating evidence indicates that body weight, alcohol and smoking are associated with psoriasis. However, these factors have scarcely been investigated in relation to onset and disease activity at onset of psoriasis.
A population-based case-control study was performed including 373 cases with onset of first-time plaque psoriasis within 12 months and matched healthy controls. Psoriasis activity was measured using the Psoriasis Area and Severity Index (PASI). Analyses were performed using conditional logistic regression. In multivariable analyses for each unit increment in body mass index, there was statistically significant 9% increased risk for psoriasis onset and 7% higher risk for increased PASI. Obesity (body mass index ≥ 30) compared with normal body weight was associated with a two-fold increased risk for psoriasis onset. Smoking was associated with a 70% increased risk for onset, but was not related to PASI. A positive association with alcohol drinking was observed among men, but not among women.
No associations were observed for weight gain and use of smokeless tobacco. Our results indicate that excessive body weight and smoking are risk factors for onset of psoriasis and that higher body mass index increases the PASI of plaque psoriasis at onset.
I wonder whether they asked the people in the survey if they had used cortisone creams to treat their psoriasis. I suspect that prolonged use causes obesity or increases your chance of becoming obese and that the psoriasis is just worse for people who have lived with it longer. Alternatively, the disease or the stressor that causes psoriasis to worsen also causes weight gain in some people.
Not sure if it’s just me, but I seem to become more iron deficient when my psoriasis gets worse, which makes me too tired to exercise.
Hello, what medication did you use? I find that topical creams or tar cleansers work for mine, but I usually only have one or 2 nails affected at a time. I combine or alternate an antifungal cream with a 0.5% hydrocortisone cream and avoid any harsh soaps. I clean the nail and rub the cream over it and leave some under it too.
Hello, I am looking for answers to my case, I have psoriasis exclusively on nails and toes, no pain but the appearance is bad. How can I control the evolution of the disease, I tried some medication but I have not noticed any change.
I appreciate your reaction, if necessary I can send some pictures.
(auto-translated from Spanish)